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Dentaljuce Shorts: 500 words, 10 MCQs, on general medicine and surgery.


Schistosomiasis, also known as snail fever, bilharzia, and Katayama fever, is a disease caused by parasitic flatworms called schistosomes. It primarily affects the urinary tract or intestines, with symptoms including abdominal pain, diarrhoea, bloody stool, and blood in the urine. Prolonged infection may result in liver damage, kidney failure, infertility, or bladder cancer. Children may experience poor growth and learning difficulties. The disease is spread through contact with freshwater contaminated by the parasites, which are released from infected snails.

Signs and Symptoms

Cercarial dermatitis
Red, maculopapular rash due to cercarial penetration.
Skin blisters
Skin blisters on the forearm created by the entrance of Schistosoma parasites.

Many individuals remain asymptomatic. Symptoms, if they appear, typically manifest 4–6 weeks post-infection. Initial symptoms may include general malaise, tingling, or a light rash known as "swimmer's itch." Acute schistosomiasis (Katayama fever) may occur weeks to months after infection, presenting symptoms like fever, muscle aches, and cough. Chronic infection can lead to more severe complications such as intestinal or urogenital schistosomiasis, hepatosplenic schistosomiasis, pulmonary schistosomiasis, and neuroschistosomiasis.


Schistosoma parasite eggs
High-powered micrograph of Schistosoma parasite eggs in human bladder tissue.
S. japonicum eggs in hepatic portal tract
S. japonicum eggs in hepatic portal tract.

Diagnosis is primarily confirmed by identifying parasite eggs in stool or urine samples using microscopic examination. Antibody detection can be useful for individuals who have travelled to endemic areas but do not show eggs in their samples. Polymerase chain reaction (PCR) testing is accurate but not widely used in low-resource settings due to cost. Imaging techniques like ultrasound, CT, and MRI can assess organ damage and severity of infection.

Transmission and Life Cycle

Life cycle of Schistosoma spp.
Life cycle of Schistosoma spp.
Lifecycle stages of Schistosoma japonicum
Lifecycle stages of Schistosoma japonicum.

Schistosomiasis is transmitted when individuals come into contact with contaminated freshwater. The lifecycle involves multiple stages, including the release of eggs into water through faeces or urine, infection of freshwater snails, and release of infectious larvae (cercariae) that penetrate human skin.


Warning sign
Warning sign in Honghu, Hubei, China, cautioning against entering water contaminated with schistosomes.

Preventive measures include improving access to clean water and sanitation, educating communities about hygiene, and using molluscicides to reduce snail populations. The World Health Organisation recommends preventive anthelminthic administration, treating entire populations in high-risk areas using praziquantel.


Ethiopian children treated
Ethiopian children treated for Schistosoma mansoni.

The primary treatment for schistosomiasis is praziquantel, which is effective against adult schistosomes but not the eggs or immature worms. Repeated treatment may be necessary to ensure complete eradication. Oxamniquine is an alternative for S. mansoni infections. Treatment guidelines by the WHO recommend different strategies based on the prevalence of symptoms in a community.


Schistosomiasis endemic countries
Geographic representation of schistosomiasis endemic countries and their preventive chemotherapy requirement status in 2020 from the World Health Organisation.
Deaths from schistosomiasis
Deaths from schistosomiasis per million persons in 2012.

Schistosomiasis is prevalent in tropical regions, particularly in Africa, Asia, and South America. In 2019, it affected approximately 236.6 million people globally. The disease is a significant public health concern, second only to malaria among parasitic diseases in terms of socio-economic impact. Death estimates vary, with the WHO estimating up to 200,000 annual deaths related to schistosomiasis.

Self-assessment MCQs (single best answer)

What is the primary cause of schistosomiasis?

Which symptom is NOT typically associated with schistosomiasis?

How is schistosomiasis primarily transmitted?

What is the initial symptom of schistosomiasis known as "swimmer's itch" caused by?

Which diagnostic method is primarily used to confirm schistosomiasis?

Which drug is commonly used to treat schistosomiasis?

What is the purpose of using molluscicides in schistosomiasis prevention?

What severe complication can result from prolonged schistosomiasis infection?

Which organisation recommends the use of preventive anthelminthic administration in high-risk areas for schistosomiasis?

In which regions is schistosomiasis most prevalent?


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